Broadstreet will be presenting our research on a number of projects at the ISPOR Europe conference in Copenhagen this year. As well, we are looking forward to learning what’s new in the use of real-world evidence and other hot topics in health economics and outcomes research.

We have seven posters at the conference this year, on subjects ranging from caregiver experiences with Friedreich ataxia to an exploration of the average expenditures per response obtained with treatment for cervical dystonia in Canada.

We are particularly pleased to be presenting our own research exploring considerations and methodologies when reference arms with varying routes of administration (e.g., oral, intravenous, subcutaneous) are pooled during the conduct of a network meta-analysis (NMA). NMAs are very frequently required in health technology assessment submissions, and it’s important to understand how combining reference arms with different methods of drug administration could influence the results of the analysis. Through a comprehensive review of recently published NMAs, we looked at how often this occurs and how this potential source of bias was addressed in these studies. Come and visit us during Poster session 4 to hear more about our results and conclusions.

We invite you to check out all our posters:

Monday 13 November – Poster session 1

EE46: BoNT-As for cervical dystonia: cost of treatment and response to therapy in Canadian patients

Johnston K¹, Griffin E1, Privolnev Y^2
1Broadstreet Health Economics & Outcomes Research, Vancouver, BC, Canada, ²Ipsen Biopharmaceuticals, Mississauga, ON, Canada

Monday 13 November – Poster session 2

PCR84: The daily life and psychosocial impacts of Friedreich Ataxia: a qualitative study of patient lived experiences

Bever A¹, Szabo SM¹, Vallortigara J², Giunti P², Lynch D³, Vasco G⁴, Tomazos I^5
1Broadstreet Health Economics & Outcomes Research, Vancouver, BC, Canada, ²Ataxia Centre, London, London, UK, ³CHOP, Philadelphia, PA, USA, ⁴Bambino Gesù Children’s Hospital, Rome, Italy, ⁵PTC Therapeutics Inc, South Plainfield, NJ, USA

Tuesday 14 November – Poster session 3

CO105: A retrospective study characterizing age at loss of ambulation among patients with Friedreich Ataxia using health administrative claims data in the United States

Salvucci A¹, Qian C², Powell L², Lynch D³, Vasco G⁴, Johnston K², Tomazos I^1
1PTC Therapeutics, South Plainfield, NJ, USA, ²Broadstreet Health Economics & Outcomes Research, Vancouver, BC, Canada, ³CHOP, Philadelphia, PA, USA, ⁴Bambino Gesù Children’s Hospital, Rome, Italy

PCR139: ‘We have conversations that other couples don’t have to have’: A qualitative study of the impact of caregiving in Friedreich ataxia

Szabo SM;¹ Bever A;¹ Lynch D;² Vasco G;³ Giunti P;⁴ Vallortigara J;⁴ Tomazos I^5
1Broadstreet Health Economics & Outcomes Research, Vancouver, BC, Canada P ²CHOP, Philadelphia, PA, USA, ³Bambino Gesù Children’s Hospital, Rome, Italy, ⁴Ataxia Centre, London, London, UK, ⁵PTC Therapeutics Inc, South Plainfield, NJ, USA

Tuesday 14 November – Poster session 4

CO142: A retrospective study characterizing age at key clinical disease indicators among patients with Friedreich Ataxia using health administrative claims data in the United States

Salvucci A¹, Qian C², Powell L², Lynch D³, Vasco G⁴, Johnston K², Tomazos I^1
1PTC Therapeutics, South Plainfield, NJ, USA; ²Broadstreet HEOR, Vancouver, BC, Canada; ³Division of Neurology, CHOP, Phila, PA; ⁴Department of Neurorehabilitation and Robotics, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

SA67: Considerations for including different routes of administration in network meta-analysis: a comprehensive review

Powell L, Friesen M, O’Sullivan F, Popoff E
Broadstreet Health Economics & Outcomes Research, Vancouver, BC, Canada

PCR192: Content validity of the EQ-5D and Health Utilities Index (HUI) to assess health-related quality-of-life (HRQoL) impact in Duchenne Muscular Dystrophy (DMD)

Szabo S¹, Audhya I², Griffin E¹, Crabtree M¹, Patel S², Bever A¹, Iannaccone ST³, Gooch K^2
1Broadstreet Health Economics & Outcomes Research, Vancouver, BC, Canada, ²Sarepta Therapeutics, Inc., Cambridge, MA, USA, ³University of Texas Southwestern Medical Center, Dallas, TX, USA

See you in Copenhagen!